Article
Nucleosome position-dependent and -independent activation of HIS7 epression in Saccharomyces cerevisiae by different transcriptional activators.
Eukaryotic cell - 1 Oct 2003
Valerius Oliver, Brendel Cornelia, Wagner Claudia, Krappmann Sven, Thoma Fritz, Braus Gerhard H
Abstract excerpt
ARO4 and HIS7 are two tandemly orientated genes of Saccharomyces cerevisiae that are transcribed into the same direction. The ARO4 terminator and the HIS7 promoter regions are sensitive to Micrococcus nuclease (Mnase) and separated by a positioned nucleosome. The HIS7 promoter is target for the transcription factors Gcn4p and Bas1p/Bas2p that activate its transcription upon amino acid starvation and purine...
Topics
- 3-Deoxy-7-Phosphoheptulonate Synthase
- Adenine
- Adenosine Triphosphatases
- Aldehyde-Lyases
- Aminohydrolases
- Blotting, Northern
- Blotting, Southern
- Chromatin
- DNA, Intergenic
- DNA-Binding Proteins