Nucleosome structure of the yeast CHA1 promoter: analysis of activation-dependent chromatin remodeling of an RNA-polymerase-II-transcribed gene in TBP and RNA pol II mutants defective in vivo in response to acidic activators.

doi:10.1093/emboj/17.20.6028

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Article

Nucleosome structure of the yeast CHA1 promoter: analysis of activation-dependent chromatin remodeling of an RNA-polymerase-II-transcribed gene in TBP and RNA pol II mutants defective in vivo in response to acidic activators.

The EMBO journal - 15 Oct 1998

Moreira J M, Holmberg S

Abstract excerpt

The Saccharomyces cerevisiae CHA1 gene encodes the catabolic L-serine (L-threonine) dehydratase. We have previously shown that the transcriptional activator protein Cha4p mediates serine/threonine induction of CHA1 expression. We used accessibility to micrococcal nuclease and DNase I to determine...

Topics

Chromatin
DNA-Binding Proteins
Fungal Proteins
Genes, Fungal
L-Serine Dehydratase
Mutation
Nucleosomes
Promoter Regions, Genetic
RNA Polymerase II
Saccharomyces cerevisiae
Saccharomyces cerevisiae Proteins
Serine
Silent Information Regulator Proteins, Saccharomyces cerevisiae

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TATA Box

TATA-Box Binding Protein

Threonine Dehydratase

Trans-Activators

Transcription Factors

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Identifiers

PMID: 9774346
DOI: 10.1093/emboj/17.20.6028
PMCID: PMC1170929

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9774346-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.