Article
RAP1 is required for BAS1/BAS2- and GCN4-dependent transcription of the yeast HIS4 gene.
Molecular and cellular biology - 1 Jul 1991
Devlin C, Tice-Baldwin K, Shore D, Arndt K T
Abstract excerpt
The major in vitro binding activity to the Saccharomyces cerevisiae HIS4 promoter is due to the RAP1 protein. In the absence of GCN4, BAS1, and BAS2, the RAP1 protein binds to the HIS4 promoter in vivo but cannot efficiently stimulate HIS4 transcription. RAP1, which binds adjacently to BAS2 on th...
Topics
- Base Sequence
- Binding Sites
- DNA-Binding Proteins
- Fungal Proteins
- GTP-Binding Proteins
- Genes, Fungal
- Genotype
- Homeodomain Proteins
- Molecular Sequence Data
- Mutagenesis, Site-Directed
- Oligonucleotide Probes
- Plasmids
- Promoter Regions, Genetic
- Protein Kinases
- Proto-Oncogene Proteins
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins
- Trans-Activators