Article
Interaction of transcriptional regulators with specific nucleosomes across the Saccharomyces genome.
Molecular cell - 24 Sept 2009
Koerber R Thomas, Rhee Ho Sung, Jiang Cizhong, Pugh B Franklin
Abstract excerpt
A canonical nucleosome architecture around promoters establishes the context in which proteins regulate gene expression. Whether gene regulatory proteins that interact with nucleosomes are selective for individual nucleosome positions across the genome is not known. Here, we examine on a genomic scale several protein-nucleosome interactions, including those that (1) bind histones (Bdf1/SWR1 and Srm1), (2) bind...
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