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Article

Intercellular adhesion molecule-1: a protective haplotype against multiple sclerosis.

Genes and immunity - 1 Oct 2003

Cournu-Rebeix I, Génin E, Lesca G, Azoulay-Cayla A, Tubridy N, Noé E, Clanet M, Edan G, Clerget-Darpoux F, Sémana G, Fontaine B

Abstract excerpt

Intercellular adhesion molecule-1 (ICAM-1) and its receptors are adhesion molecules that play a key role in the transmigration of inflammatory cells through the blood-brain barrier, one of the earliest events in multiple sclerosis (MS), which leads to demyelination in the central nervous system. To investigate the role of genes encoding ICAM-1 and its receptors, we used a strategy of genetic linkage and...

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PMID: 14551606
DOI: 10.1038/sj.gene.6364009

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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