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Article

Overproduction of highly active trypanosome alternative oxidase in Escherichia coli heme-deficient mutant.

Parasitology international - 1 Sept 2003

Fukai Yoshihisa, Nihei Coichi, Kawai Keisuke, Yabu Yoshisada, Suzuki Takasi, Ohta Nobuo, Minagawa Nobuko, Nagai Kazuo, Kita Kiyoshi

Abstract excerpt

Cyanide-insensitive trypanosome alternative oxidase (TAO) is the terminal oxidase of the respiratory chain of long slender bloodstream forms of the African trypanosome, which causes sleeping sickness in humans and nagana in cattle. TAO has been targeted for the development of anti-trypanosomal drugs, because it does not exist in the host. In this study, we established a system for overproduction of highly active...

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PMID: 14550479
DOI: 10.1016/s1383-5769(03)00007-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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