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Article

Disparate phenotypic effects from the knockdown of various Trypanosoma brucei cytochrome c oxidase subunits.

Molecular and biochemical parasitology - 1 Aug 2012

Gnipová Anna, Panicucci Brian, Paris Zdeněk, Verner Zdeněk, Horváth Anton, Lukeš Julius, Zíková Alena

Abstract excerpt

The Trypanosoma brucei cytochrome c oxidase (respiratory complex IV) is a very divergent complex containing a surprisingly high number of trypanosomatid-specific subunits with unknown function. To gain insight into the functional organization of this large protein complex, the expression of three novel subunits (TbCOX VII, TbCOX X and TbCOX 6080) were down-regulated by RNA interference. We demonstrate that all...

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PMID: 22569586
DOI: 10.1016/j.molbiopara.2012.04.013

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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