Article
PTCH mutations in squamous cell carcinoma of the skin.
The Journal of investigative dermatology - 1 Apr 2001
Ping X L, Ratner D, Zhang H, Wu X L, Zhang M J, Chen F F, Silvers D N, Peacocke M, Tsou H C
Abstract excerpt
Ultraviolet light exposure is the major risk factor for the development of squamous cell carcinoma in Caucasians. Mutations in the tumor suppressor gene p53 have been identified in both squamous cell carcinomas and basal cell carcinomas. The human homolog of the Drosophila patched gene, has been...
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