Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

p53 N-terminal Ser-15 approximately P and Ser-20 approximately P levels in squamous cell lung cancer after radio/chemotherapy.

American journal of respiratory cell and molecular biology - 1 Apr 2004

Mroz Robert M, Holownia Adam, Chyczewska Elzbieta, Chyczewski Lech, Braszko Jan J

Abstract excerpt

Functional regulation of p53 protein, a critical regulator of cell cycle and apoptosis, was investigated in fiberoptic bronchoscopy biopsy samples taken from 23 patients suffering from recurrent squamous cell lung cancer by analyzing the expression and phosphorylation status of the p53 at Ser15 and Ser20 before and after treatment with radiotherapy/cisplatin/vinorelbine. Poly(ADP-ribose) levels as a marker of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinoma, Squamous Cell
Share to Cisplatin

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Combined Modality Therapy

Share to Ki-67 Antigen

Share to Regression Analysis

Share to Serine

Share to Vinblastine

Share to Vinorelbine

Source

Identifiers

PMID: 14527925
DOI: 10.1165/rcmb.2003-0077OC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 10 closest

p53 N-terminal Ser-15 approximately P and Ser-20 approximately P levels in squamous cell lung cancer after radio/chemotherapy.PMID 14527925Read ↗

Alterations in the p53 pathway and their association with radio- and chemosensitivity in head and neck squamous cell carcinoma.Semantic proximity Read ↗

Simultaneous phosphorylation of p53 at serine 15 and 20 induces apoptosis in human glioma cells by increasing expression of pro-apoptotic genes.Semantic proximity Read ↗

Constitutive Activation of DNA Damage Checkpoint Signaling Contributes to Mutant p53 Accumulation via Modulation of p53 Ubiquitination.Semantic proximity Read ↗

Hypoxia Links ATR and p53 through Replication ArrestSemantic proximity Read ↗

Phosphorylation of serines 15 and 37 is necessary for efficient accumulation of p53 following irradiation with UV.Semantic proximity Read ↗

Molecular analysis of p53 gene in laryngeal premalignant and malignant lesions. p53 protein immunohistochemical expression is positively related to proliferating cell nuclear antigen labelling index.Semantic proximity Read ↗

A role for ATR in the DNA damage-induced phosphorylation of p53.Semantic proximity Read ↗

Expression of p53 protein in advanced head and neck squamous cell carcinoma before and after chemotherapy.Semantic proximity Read ↗

Critical role for p53-serine 15 phosphorylation in stimulating transactivation at p53-responsive promoters.Semantic proximity Read ↗

ERKs and p38 kinase phosphorylate p53 protein at serine 15 in response to UV radiation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.