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Article

Selection of a secretion-incompetent mutant in the serum of a patient with severe hepatitis B.

Gastroenterology - 1 Oct 2003

Kalinina Tatyana, Riu Anna, Fischer Lutz, Santantonio Theresa, Will Hans, Sterneck Martina

Abstract excerpt

BACKGROUND AND AIMS: A secretion-incompetent, highly replicating hepatitis B variant was previously found as the dominant viral population in the serum of a liver transplant recipient with severe hepatitis B reinfection. The secretion block resulted from mutations in the S protein, including the Gly145Arg substitution known to emerge under antibody to hepatitis B surface antigen immunoglobulin treatment. Here we...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 14517791
DOI: 10.1016/s0016-5085(03)01202-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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