Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Selection of a multiple drug-resistant hepatitis B virus strain in a liver-transplanted patient.

Gastroenterology - 1 Oct 2006

Villet Stéphanie, Pichoud Christian, Villeneuve Jean-Pierre, Trépo Christian, Zoulim Fabien

Abstract excerpt

BACKGROUND & AIMS: Sequential anti-hepatitis B virus (HBV) therapy may lead to the selection of complex mutants. We analyzed the genetic and phenotypic evolution of the viral quasispecies of a patient who received successively lamivudine, add-on adefovir+lamivudine, followed by lamivudine+adefovir+hepatitis B immunoglobulins (HBIg) after orthotopic liver transplantation. METHODS: For genotypic analysis, a 1310-bp...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenine
Share to Drug Resistance, Multiple

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hepatitis B Surface Antigens

Share to Immunoglobulins

Share to Lamivudine

Share to Liver Transplantation

Share to Organophosphonates

Share to Reverse Transcriptase Inhibitors

Source

Identifiers

PMID: 17030194
DOI: 10.1053/j.gastro.2006.08.013

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Selection of a multiple drug-resistant hepatitis B virus strain in a liver-transplanted patient.PMID 17030194Read ↗

Stepwise process for the development of entecavir resistance in a chronic hepatitis B virus infected patient.Semantic proximity Read ↗

Susceptibility to antivirals of a human HBV strain with mutations conferring resistance to both lamivudine and adefovir.Semantic proximity Read ↗

Unsuccessful therapy with adefovir and entecavir-tenofovir in a patient with chronic hepatitis B infection with previous resistance to lamivudine: a fourteen-year evolution of hepatitis B virus mutations.Semantic proximity Read ↗

Selection of hepatitis B virus (HBV) vaccine escape mutants in HBV-infected and HBV/HIV-coinfected patients failing antiretroviral drugs with anti-HBV activity.Semantic proximity Read ↗

In vitro characterization of viral fitness of therapy-resistant hepatitis B variants.Semantic proximity Read ↗

Evolution of hepatitis B virus sequence from a liver transplant recipient with rapid breakthrough despite hepatitis B immune globulin prophylaxis and lamivudine therapy.Semantic proximity Read ↗

Decreased infectivity of nucleoside analogs-resistant hepatitis B virus mutants.Semantic proximity Read ↗

Selection of a hepatitis B virus strain resistant to adefovir in a liver transplantation patientSemantic proximity Read ↗

In vitro drug susceptibility analysis of hepatitis B virus clinical quasispecies populations.Semantic proximity Read ↗

The Impact of the Hepatitis B Virus Polymerase rtA181T Mutation on Replication and Drug Resistance Is Potentially Affected by Overlapping Changes in Surface GeneSemantic proximity Read ↗

Characterization of hepatitis virus B isolated from a multi-drug refractory patient.Semantic proximity Read ↗

Characterization of multi-DAA resistance using a novel hepatitis C virus genotype 3a infectious culture system.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.