Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Sry is a transcriptional activator.

1 Sept 1994

Abstract excerpt

The SRY gene functions as a genetic switch in gonadal ridge initiating testis determination. The mouse Sry and human SRY open reading frames (ORFs) share a conserved DNA-binding domain (the HMG-box) yet exhibit no additional homology outside this region. As judged by the accumulation of lacZ-SRY hybrid proteins in the nucleus, both the human and mouse SRY ORFs contain a nuclear localization signal. The mouse Sry...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
Share to Genomics and Chromatin Dynamics
Share to Sperm and Testicular Function

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 7838151
DOI: 10.1210/mend.8.9.7838151

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Sry is a transcriptional activator.PMID 7838151Read ↗

Molecular basis of mammalian sexual determination: activation of Mullerian inhibiting substance gene expression by SRYSemantic proximity Read ↗

SRY protein function in sex determination: thinking outside the box.Semantic proximity Read ↗

SRY: A transcriptional activator of mammalian testis determinationSemantic proximity Read ↗

A conserved NR5A1-responsive enhancer regulates SRY in testis-determinationSemantic proximity Read ↗

The biochemical role of SRY in sex determinationSemantic proximity Read ↗

SEX IN THE 90s:<i>SRY</i>and the Switch to the Male PathwaySemantic proximity Read ↗

Structure–function analysis of mouse Sry reveals dual essential roles of the C-terminal polyglutamine tract in sex determinationSemantic proximity Read ↗

A naturally occurring deletion in the SRY promoter region affecting the Sp1 binding site is associated with sex reversal.Semantic proximity Read ↗

The role of SRY in mammalian sex determination.Semantic proximity Read ↗

The Molecular Action and Regulation of the Testis-Determining Factors, SRY (Sex-Determining Region on the Y Chromosome) and SOX9 [SRY-Related High-Mobility Group (HMG) Box 9]Semantic proximity Read ↗

Generation and mutational analysis of a transgenic mouse model of human SRYSemantic proximity Read ↗

Interaction of normal and mutant SRY proteins with DNA.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.