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Article

Efficient gene modulation in mouse epiblast using a Sox2Cre transgenic mouse strain.

Mechanisms of development - 1 Dec 2002

Hayashi Shigemi, Lewis Paula, Pevny Larysa, McMahon Andrew P

Abstract excerpt

We have generated a transgenic line that expresses the Cre gene product under the regulation of a 12.5 kb upstream regulatory sequence from the Sox2 gene. Using a R26R reporter line, we show that this transgenic line induces recombination in all epiblast cells by embryonic day (E) 6.5 but little...

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PMID: 14516668
DOI: 10.1016/s0925-4773(03)00099-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-14516668-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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