Article
Generation of mice harboring a Sox6 conditional null allele.
Genesis (New York, N.Y. : 2000) - 1 May 2006
Dumitriu Bogdan, Dy Peter, Smits Patrick, Lefebvre Véronique
Abstract excerpt
Sox6 belongs to the family of Sry-related HMG box transcription factors, which determine cell fate and differentiation in various lineages. Sox6 is expressed in several tissues, including cartilage, testis, neuronal, and erythropoietic tissues. Mice lacking Sox6 have revealed critical roles for Sox6 in several of these tissues, but their multiple defects and early lethality has limited studies in specific cell...
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