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Article

Conserved pore residues in the AAA protease FtsH are important for proteolysis and its coupling to ATP hydrolysis.

The Journal of biological chemistry - 12 Dec 2003

Yamada-Inagawa Tomoko, Okuno Takashi, Karata Kiyonobu, Yamanaka Kunitoshi, Ogura Teru

Abstract excerpt

Like other AAA proteins, Escherichia coli FtsH, a membrane-bound AAA protease, contains highly conserved aromatic and glycine residues (Phe228 and Gly230) that are predicted to lie in the central pore region of the hexamer. The functions of Phe228 and Gly230 were probed by site-directed mutagenes...

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Identifiers

PMID: 14514680
DOI: 10.1074/jbc.M308327200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-14514680-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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Conserved pore residues in the AAA protease FtsH are important for proteolysis and its coupling to ATP hydrolysis.PMID 14514680Read ↗

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