Article
Characterization of mutants of the Escherichia coli AAA protease, FtsH, carrying a mutation in the central pore region.
Journal of structural biology - 1 Oct 2006
Okuno Takashi, Yamanaka Kunitoshi, Ogura Teru
Abstract excerpt
Escherichia coli FtsH is an ATP-dependent and membrane-bound protease, which belongs to the ATPases associated with diverse cellular activities family. FtsH degrades a subset of cytoplasmic regulatory proteins and misassembled membrane proteins. It has been proposed that ATP-dependent proteases unfold and translocate substrate proteins into the protease chamber. Previously, we reported that Phe228 and Gly230 in...
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