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Article

An AAA protease FtsH can initiate proteolysis from internal sites of a model substrate, apo-flavodoxin.

Genes to cells : devoted to molecular & cellular mechanisms - 1 Mar 2006

Okuno Takashi, Yamanaka Kunitoshi, Ogura Teru

Abstract excerpt

Escherichia coli FtsH, which belongs to the AAA (ATPases associated with diverse cellular activities) family, is an ATP-dependent and membrane-bound protease. FtsH degrades misassembled membrane proteins and a subset of cytoplasmic regulatory proteins. It has been proposed that ATP-dependent proteases unfold substrate proteins and initiate a processive proteolysis from either terminus of the substrate...

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PMID: 16483314
DOI: 10.1111/j.1365-2443.2006.00940.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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