Article
FtsH (HflB) is an ATP-dependent protease selectively acting on SecY and some other membrane proteins.
The Journal of biological chemistry - 6 Dec 1996
Akiyama Y, Kihara A, Tokuda H, Ito K
Abstract excerpt
The FtsH protein is a membrane-bound ATPase of Escherichia coli that was proposed to be involved in membrane protein assembly as well as degradation of some unstable proteins. SecY, a subunit of protein translocase, is FtsH dependently degraded in vivo when it fails to associate with its partner...
Topics
- ATP-Dependent Proteases
- Adenosine Triphosphatases
- Adenosine Triphosphate
- Amino Acid Sequence
- Bacterial Proteins
- Binding Sites
- Electrophoresis, Polyacrylamide Gel
- Endopeptidases
- Escherichia coli Proteins
- Membrane Proteins
- Molecular Sequence Data
- Mutagenesis, Site-Directed
- Phenotype
- Plasmids
- SEC Translocation Channels