Article
Escherichia coli FtsH is a membrane-bound, ATP-dependent protease which degrades the heat-shock transcription factor sigma 32.
The EMBO journal - 1 Jun 1995
Tomoyasu T, Gamer J, Bukau B, Kanemori M, Mori H, Rutman A J, Oppenheim A B, Yura T, Yamanaka K, Niki H
Abstract excerpt
Escherichia coli FtsH is an essential integral membrane protein that has an AAA-type ATPase domain at its C-terminal cytoplasmic part, which is homologous to at least three ATPase subunits of the eukaryotic 26S proteasome. We report here that FtsH is involved in degradation of the heat-shock transcription factor sigma 32, a key element in the regulation of the E. coli heat-shock response. In the...
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