Article
Escherichia coli FtsH is a membrane-bound, ATP-dependent protease which degrades the heat-shock transcription factor sigma 32.
The EMBO journal - 1 Jun 1995
Tomoyasu T, Gamer J, Bukau B, Kanemori M, Mori H, Rutman A J, Oppenheim A B, Yura T, Yamanaka K, Niki H
Abstract excerpt
Escherichia coli FtsH is an essential integral membrane protein that has an AAA-type ATPase domain at its C-terminal cytoplasmic part, which is homologous to at least three ATPase subunits of the eukaryotic 26S proteasome. We report here that FtsH is involved in degradation of the heat-shock tran...
Topics
- ATP-Dependent Proteases
- Adenosine Triphosphatases
- Bacterial Proteins
- Binding Sites
- Cations, Divalent
- Escherichia coli
- Escherichia coli Proteins
- Gene Expression Regulation, Bacterial
- Genes, Bacterial
- Heat-Shock Proteins
- Membrane Proteins
- Mutation
- Nucleotides