Article
Insulin affects vascular smooth muscle cell phenotype and migration via distinct signaling pathways.
Diabetes - 1 Oct 2003
Wang Cecilia C Low, Gurevich Inga, Draznin Boris
Abstract excerpt
Insulin maintains vascular smooth muscle cell (VSMC) quiescence yet can also promote VSMC migration. The mechanisms by which insulin exerts these contrasting effects were examined using alpha-smooth muscle actin (alpha-SMA) as a marker of VSMC phenotype because alpha-SMA is highly expressed in qu...
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