Article
Type 2 diabetes impairs venous, but not arterial smooth muscle cell function: possible role of differential RhoA activity.
Cardiovascular revascularization medicine : including molecular interventions - 1 Apr 2014
Riches Kirsten, Warburton Philip, O'Regan David J, Turner Neil A, Porter Karen E
Abstract excerpt
BACKGROUND/PURPOSE: Coronary heart disease is the leading cause of morbidity in patients with type 2 diabetes mellitus (T2DM), frequently resulting in a requirement for coronary revascularization using the internal mammary artery (IMA) or saphenous vein (SV). Patency rates of SV grafts are inferior to IMA and further impaired by T2DM whilst IMA patencies appear similar in both populations. Smooth muscle cells...
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