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Article

Sequence analysis and high-throughput immunohistochemical profiling of KIT (CD 117) expression in uveal melanoma using tissue microarrays.

Virchows Archiv : an international journal of pathology - 1 Dec 2003

Pache Mona, Glatz Katharina, Bösch Doris, Dirnhofer Stephan, Mirlacher Martina, Simon Ronald, Schraml Peter, Rufle Alex, Flammer Josef, Sauter Guido, Meyer Peter

Abstract excerpt

We aimed to immunohistochemically examine the expression of KIT (CD 117) in human posterior uveal melanoma and to analyze KIT-positive tumors for gene mutations. Brought into a tissue microarray (TMA) format were 101 formalin-fixed, paraffin-embedded posterior uveal melanomas. Immunohistochemistry was performed using the polyclonal anti-CD117 antibody from Dako (A4502). In ten selected KIT-positive tumors, exons...

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Identifiers

PMID: 14513377
DOI: 10.1007/s00428-003-0883-2

Genes

KIT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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