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Article

KIT mutations and CD117 overexpression are markers of better progression-free survival in vulvar melanomas.

The British journal of dermatology - 1 Nov 2017

Dias-Santagata D, Selim M A, Su Y, Peng Y, Vollmer R, Chłopik A, Tell-Marti G, Paral K M, Shalin S C, Shea C R, Puig S, Fernandez-Figueras M T, Biernat W, Ryś J, Marszalek A, Hoang M P

Abstract excerpt

BACKGROUND: Few studies have addressed prognostic markers and none has correlated molecular status and prognosis in vulvar melanomas. OBJECTIVES: To evaluate the clinicopathological features of 95 cases of vulvar melanoma. METHODS: p53, CD117, Ki-67, neurofibromin, brafv600e and nrasq61r immunostains, and molecular analyses by either targeted next-generation or direct sequencing, were performed on available...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Proto-Oncogene Proteins B-raf

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Source

Identifiers

PMID: 28734009
DOI: 10.1111/bjd.15836

Genes

KIT
NRAS
BRAF
TERT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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