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Article

KIT Somatic Mutations and Immunohistochemical Expression in Canine Oral Melanoma

10 Dec 2020

Abstract excerpt

Canine oral melanoma (COM) is an aggressive neoplasm with a low response to therapies, sharing similarities with human mucosal melanomas. In the latter, significant alterations of the proto-oncogene KIT have been shown, while in COMs only its exon 11 has been adequately investigated. In this study, 14 formalin-fixed, paraffin-embedded COMs were selected considering the following inclusion criteria: unequivocal...

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PMID: 33321993
DOI: 10.3390/ani10122370

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