Article
Analysis of KIT mutations and c-KIT expression in Chinese Uyghur and Han patients with melanoma.
Clinical and experimental dermatology - 1 Jan 2016
Kang X-J, Shi X-H, Chen W-J, Pu X-M, Sun Z-Z, Halifu Y, Wu X-J, Yu S-R, Liu W-X, Liang J-Q, Luo D, Ren D-Y
Abstract excerpt
BACKGROUND: The KIT gene plays an important role in the pathogenesis of malignant melanoma (MM). In recent years, activating mutations in KIT have been recognized as oncogenic. A number of therapies have been established, which provide significant clinical benefits for patients with MM with KIT mutations. Thus, detection of KIT mutations can have profound therapeutic implications. AIM: To investigate KIT gene...
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