Article
Genetic recombination during coinfection of two mutants of human respiratory syncytial virus.
Journal of virology - 1 Oct 2003
Spann Kirsten M, Collins Peter L, Teng Michael N
Abstract excerpt
Recombination between coinfecting viruses had not been documented previously for a nonsegmented negative-strand RNA virus (mononegavirus). We investigated the potential of intermolecular recombination by respiratory syncytial virus (RSV) by coinfecting HEp-2 cells with two recombinant RSV (rRSV) mutants lacking either the G gene (DeltaG/HEK) or the NS1 and NS2 genes (DeltaNS1/2). These viruses replicate...
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