Article
Experimental evidence of recombination in murine noroviruses.
The Journal of general virology - 1 Nov 2010
Mathijs Elisabeth, Muylkens Benoît, Mauroy Axel, Ziant Dominique, Delwiche Thomas, Thiry Etienne
Abstract excerpt
Based on sequencing data, norovirus (NoV) recombinants have been described, but no experimental evidence of recombination in NoVs has been documented. Using the murine norovirus (MNV) model, we investigated the occurrence of genetic recombination between two co-infecting wild-type MNV isolates in RAW cells. The design of a PCR-based genotyping tool allowed accurate discrimination between the parental genomes and...
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