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Dynamics of HIV-1 recombination in its natural target cells

9 Mar 2004

Abstract excerpt

Genetic recombination is believed to assist HIV-1 diversification and escape from host immunity and antiviral therapies, yet this process remains largely unexamined within the natural target-cell populations. We developed a method for measuring HIV-1 recombination directly that employs reporter viruses bearing functional enhanced yellow fluorescent protein (YFP) and enhanced cyan fluorescent protein (CFP) genes...

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PMID: 15010526
DOI: 10.1073/pnas.0306764101

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