Article
ABCC5 Gene Variant c.1146A>G Reduces MRP5 Expression and Can be a Potential Marker to Manage Cilostazol Induced Headache
2020-03-23
Abstract excerpt
<title>Abstract</title> <p><bold>Background:</bold> Patients taking cilostazol, a representative phosphodiesterase type III inhibitor used for vasodilation, occasionally complain of headaches. Cerebral arteriolar relaxation, due to an increase in intracellular cAMP or cGMP, is believed to be associated with a severe form of cilostazol-induced headaches. Multidrug resistance protein 5 (MRP5) is an important regula...
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Identifiers and source
- Literature Corpus work
- 5e2939ae-11c6-52f3-80d9-881d26985b04
- DOI
- 10.21203/rs.3.rs-18650/v1
