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Article

Identification and characterization of the canine multidrug resistance-associated protein.

Molecular cancer therapeutics - 1 Dec 2002

Ma Liandong, Pratt Susan E, Cao Jin, Dantzig Anne H, Moore Robert E, Slapak Christopher A

Abstract excerpt

Human multidrug resistance protein 1 (MRP1) confers resistance to the Vinca alkaloids, the anthracyclines, and the epipodophyllotoxins. It is also capable of binding to and transporting the glutathione S-conjugate leukotriene C4 (LTC4) in isolated membrane vesicles. To explore species differences that exist between MRP orthologs, we cloned and characterized the mRNA encoding a canine ortholog of human...

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PMID: 12516967

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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