Article
BetaS-haplotypes in sickle cell anemia patients from Salvador, Bahia, Northeastern Brazil.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas - 1 Oct 2003
Gonçalves M S, Bomfim G C, Maciel E, Cerqueira I, Lyra I, Zanette A, Bomfim G, Adorno E V, Albuquerque A L, Pontes A, Dupuit M F, Fernandes G B, dos Reis M G
Abstract excerpt
BetaS-Globin haplotypes were studied in 80 (160 betaS chromosomes) sickle cell disease patients from Salvador, Brazil, a city with a large population of African origin resulting from the slave trade from Western Africa, mainly from the Bay of Benin. Hematological and hemoglobin analyses were carried out by standard methods. The betaS-haplotypes were determined by PCR and dot-blot techniques. A total of 77 (48.1%)...
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