Article
Analysis of betaS and betaA genes in a Mexican population with African roots.
Blood cells, molecules & diseases - 1 Jan 2000
Magaña María Teresa, Ongay Zoyla, Tagle Juan, Bentura Gilberto, Cobián José G, Perea F Javier, Casas-Castañeda Maricela, Sánchez-López Yoaly J, Ibarra Bertha
Abstract excerpt
To investigate the origin of the beta(A) and beta(S) genes in a Mexican population with African roots and a high frequency of hemoglobin S, we analyzed 467 individuals (288 unrelated) from different towns in the states of Guerrero and Oaxaca in the Costa Chica region. The frequency of the sickle-cell trait was 12.8%, which may represent a public health problem. The frequencies of the beta-haplotypes were...
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