Article

Clinical and molecular characteristics of sickle cell anemia in the northeast of Brazil

2008-01-01

Abstract excerpt

Beta S-globin gene (βS-globin) haplotypes, markers for severe sickle cell anemia (SCA), and the alpha-thalassemia 2 gene 3.7 kb deletion (-α2(3.7 kb) thal) along with demographic and clinical data were investigated in SCA outpatients (n = 125, 63 female and 62 male) in the Brazilian state of Bahia, which has a high prevalence SCA. PCR-RFLP showed that the Central African Republic/Benin (CAR/BEN, 51.2%) haplotype w...

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Literature Corpus work: a0232d6d-741f-5e12-a5bc-96df3128ae05
DOI: 10.1590/s1415-47572008000400003

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