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Article

The beta-globin gene cluster haplotypes in sickle cell anemia patients from Northeast Brazil: a clinical and molecular view.

Hemoglobin - 1 Aug 2004

Adorno Elisângela Vitória, Zanette Angela, Lyra Isa, Souza Cyntia Cajado, Santos Leandro Ferraz, Menezes Joelma Figueiredo, Dupuit Marie France, Almeida Mari Ney Tavares, Reis Mitermayer Galvão, Gonçalves Marilda Souza

Abstract excerpt

The beta(S)-globin haplotypes were studied in 78 sickle cell Brazilian patients from Bahia, Northeast Brazil, that has a large population of African origin. Hemoglobin (Hb) profiles were developed by high-performance liquid chromatography (HPLC), and beta(S)-globin gene haplotypes were determined by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) techniques. We identified 44 (55.0%)...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 15481897
DOI: 10.1081/hem-120040310

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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