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Article

Molecular signatures of anti-nuclear antibodies: contributions of specific light chain residues and a novel New Zealand Black V kappa 1 germline gene.

Journal of immunology (Baltimore, Md. : 1950) - 1 Oct 2003

Liang Zhiyan, Chen Cui, Mohan Chandra

Abstract excerpt

Although the Ig H chains of anti-nuclear Abs (ANA) have been described to possess certain shared molecular signatures, it remains unclear whether the L chains of these Abs also possess distinctive molecular features. The present study examines this by generating and analyzing two comprehensive murine Ig L chain databases, one consisting of 264 monoclonal ANAs and the other consisting of 145 non-ANAs, drawn from...

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Share to Antibodies, Antinuclear
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gene Rearrangement, B-Lymphocyte, Light Chain

Share to Immunoglobulin Joining Region

Share to Immunoglobulin kappa-Chains

Share to Immunoglobulin Light Chains

Share to Mice, Inbred NZB

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Source

Identifiers

PMID: 14500691
DOI: 10.4049/jimmunol.171.7.3886

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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