Article
Steel-Dickie (Sld) mutation affects both maintenance and differentiation of testicular germ cells in mice.
Journal of reproduction and fertility - 1 Mar 1991
Tajima Y, Sakamaki K, Watanabe D, Koshimizu U, Matsuzawa T, Nishimune Y
Abstract excerpt
The effects of Steel-Dickie (Sld) mutations on testicular germ cell differentiation were investigated using experimental cryptorchidism and its surgical reversal in mutant, C57BL/6-Sld/+ and wild-type C57BL/6- +/+ mice. In Sld/+ cryptorchid testes the maintenance of undifferentiated type-A spermatogonia was impaired and their numbers decreased. In contrast, the proliferative activity of type-A spermatogonia in...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
