Article
Identification of a binding protein to the X gene promoter region of hepatitis B virus.
Virology - 1 Dec 1992
Nakamura I, Koike K
Abstract excerpt
The X protein of hepatitis B virus (HBV) is a transactivator to homologous and heterologous viral and cellular transcriptional regulatory elements. One sequence-specific binding protein, whose binding site located from nt 1102 to nt 1117 of HBV DNA, was identified by mobility shift assay and DNase I foot-printing analysis. A CAT assay experiment demonstrated this 16-bp binding site to have a promoter activity in...
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