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Article

A negative regulatory element and its binding protein in the upstream of enhancer II of hepatitis B virus.

DNA and cell biology - 1 Dec 1997

Park G T, Yi Y W, Choi C Y, Rho H M

Abstract excerpt

The hepatitis B virus (HBV) core/pregenomic promoter is regulated by enhancer I (ENI) and enhancer II (ENII) which are located upstream of the initiation sites of core/pregenomic transcripts. In this study, we identified a negative regulatory element (NRE) (nt 1576 to 1639) upstream of ENII by serial deletion analysis; a 33 kDa cellular protein in HepG2 cells binds to this element. The NRE has a significant...

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Source

Identifiers

PMID: 9428794
DOI: 10.1089/dna.1997.16.1459

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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