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Hepatitis B virus X protein enhances NFκB activity through cooperating with VBP1

29 Feb 2008

Abstract excerpt

Hepatitis B virus X protein (HBx) is essential for hepatitis B virus infection and exerts a pleiotropic effect on various cellular machineries. HBx has been also demonstrated as an indirect transcriptional transactivator of various different viral and cellular promoters. In addition, HBx is involved in the development of various liver diseases including hepatocellular carcinoma. However the mechanism of HBx in...

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PMID: 18315953
DOI: 10.5483/bmbrep.2008.41.2.158

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