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Article

Transactivation by the hepatitis B virus X protein depends on AP-2 and other transcription factors.

Nature - 1 Mar 1990

Seto E, Mitchell P J, Yen T S

Abstract excerpt

The hepatitis B virus (HBV) X gene product (pX) could be important in disease pathogenesis because it is known to transactivate transcription from many viral and cellular gene promoters, including the HBV core gene promoter, the human immunodeficiency virus (HIV-1) long terminal repeat, and the c-myc promoter. We have previously shown that only a subset of the promoters that can be transactivated by pX is...

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PMID: 2154703
DOI: 10.1038/344072a0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Transactivation by the hepatitis B virus X protein depends on AP-2 and other transcription factors.PMID 2154703Read ↗

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Human hepatitis virus X gene encodes a regulatory domain that represses transactivation of X protein.Semantic proximity Read ↗

Hepatitis B virus X protein inhibits nucleotide excision repairSemantic proximity Read ↗

Hepatitis B virus transcriptional activators: mechanisms and possible role in oncogenesisSemantic proximity Read ↗

Hepatitis B virus X protein interferes with cellular DNA repair.Semantic proximity Read ↗

Mutual functional antagonism of the simian virus 40 T antigen and the hepatitis B virus trans activator.Semantic proximity Read ↗

Hepatitis B virus transactivator HBx uses a tumour promoter signalling pathwaySemantic proximity Read ↗

Different regions of hepatitis B virus X protein are required for enhancement of bZip-mediated transactivation versus transrepression.Semantic proximity Read ↗

pX, the HBV-encoded coactivator, suppresses the phenotypes of TBP and TAFII250 mutants.Semantic proximity Read ↗

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