Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Relationship between serum concentration and dose of valproic acid during monotherapy in adult outpatients.

Therapeutic drug monitoring - 1 Oct 1992

Tisdale J E, Tsuyuki R T, Oles K S, Penry J K

Abstract excerpt

The relationship between serum concentration and dose of valproic acid (VPA) is reported to be variable and inconsistent. However, studies evaluating this relationship have included individuals of varying ages and patients receiving potentially interacting medications. In this study, the relationship between VPA serum concentration and dose was evaluated in a homogeneous patient population. Medical records of 60...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Dose-Response Relationship, Drug
Share to Epilepsy

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genetic Variation

Source

Identifiers

PMID: 1448851
DOI: 10.1097/00007691-199210000-00013

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Relationship between serum concentration and dose of valproic acid during monotherapy in adult outpatients.PMID 1448851Read ↗

Genetic polymorphisms and valproic acid plasma concentration in children with epilepsy on valproic acid monotherapy.Semantic proximity Read ↗

Impact of age, gender and CYP2C9/2C19 genotypes on dose-adjusted steady-state serum concentrations of valproic acid-a large-scale study based on naturalistic therapeutic drug monitoring data.Semantic proximity Read ↗

Valproic Acid: Special Considerations and Targeted Monitoring.Semantic proximity Read ↗

Influence of UGT2B7 and UGT1A6 polymorphisms on plasma concentration to dose ratio of valproic acid in Chinese epileptic children.Semantic proximity Read ↗

Determination of the Optimal Concentration of Valproic Acid in Patients with Epilepsy: A Population Pharmacokinetic-Pharmacodynamic Analysis.Semantic proximity Read ↗

Effect of carbapenem and VPA coadministration on seizure outcomes: a retrospective single-center studySemantic proximity Read ↗

Effect of UGT1A6 and UGT2B7 polymorphisms on the valproic acid serum concentration and drug-induced liver injury.Semantic proximity Read ↗

Effect of UGT2B7 genotypes on plasma concentration of valproic acid: a meta-analysis.Semantic proximity Read ↗

Interindividual variation of plasma haloperidol concentrations and the impact of concomitant medications: the analysis of therapeutic drug monitoring data.Semantic proximity Read ↗

Just Say No to Postmortem Drug Dose CalculationsSemantic proximity Read ↗

Serum concentrations and side effects in psychiatric patients during risperidone therapy.Semantic proximity Read ↗

Biologic variation of serum and salivary lithium.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.