Article
Frequency of H-ras mutations in human bladder cancer detected by direct sequencing.
British journal of urology - 1 May 1994
Burchill S A, Neal D E, Lunec J
Abstract excerpt
OBJECTIVE: To determine the frequency of mutations of the H-ras gene in transitional cell carcinomas of the human urinary bladder using direct DNA sequencing based on the polymerase chain reaction (PCR) method and to compare the results with those of other methods. In addition, the relationship of the mutation frequency to tumour stage and grade was examined. PATIENTS AND METHODS: Bladder tumour samples, taken by...
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