Article
Two-locus models of disease.
Genetic epidemiology - 1 Jan 1992
Neuman R J, Rice J P
Abstract excerpt
Most complex diseases have not been amenable to genetic analysis under the assumption of single locus or multifactorial models. Consequently, interest has turned to the consideration of the properties of oligogenic models. i.e., genetic models involving a small number of genes. Nine two-locus mod...
Topics
- Bipolar Disorder
- Epistasis, Genetic
- Gene Frequency
- Genetic Diseases, Inborn
- Genetic Variation
- Humans
- Mathematics
- Models, Genetic
- Prevalence
- Recurrence
- Risk Factors
- Schizophrenia