Estimation of disease risk under bivariate models of multifactorial inheritance.

doi:10.1002/gepi.1370070507

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Article

Estimation of disease risk under bivariate models of multifactorial inheritance.

Genetic epidemiology - 1 Jan 1990

Moldin S O, Rice J P, Van Eerdewegh P, Gottesman I I, Erlenmeyer-Kimling L

Abstract excerpt

Adjunct consideration of both qualitative (affection status) and quantitative (correlated liability indicator) information to define a bivariate phenotype can increase considerably the accuracy and efficiency of disease risk estimation. A general approach for calculating morbid risks to offspring...

Topics

Mathematics
Models, Genetic
Phenotype
Risk
Schizophrenia
Software

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