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Article

Evidence and implications for multiplicative interactions among loci predisposing to human common disease.

Human heredity - 1 Jan 2005

Jones Hywel B, Faham Malek

Abstract excerpt

OBJECTIVE: The aim of this study was to utilize information on monozygotic twin concordance rates and linkage studies results for common diseases to predict the likely mode of interaction between susceptibility loci. METHODS: We calculated combinations of allele frequency and genotypic relative risk (GRR) that would generate linkage results typically observed in common human diseases. Given these single locus...

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PMID: 15942249
DOI: 10.1159/000086118

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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