Article
Molecular analysis of anti-idiotypic monoclonal antibodies in the HLA-DR antigenic system.
European journal of immunology - 1 Nov 1992
Armandola E A, Mariani S M, Zwickl M, Hardman N, Ferrone S
Abstract excerpt
The structural organization of anti-idiotypic (id) antibodies has been investigated mostly in haptenic systems. No information is available about the structural characteristics of anti-id antibodies in major histocompatibility complex (MHC) antigenic systems, although these data may contribute to our understanding of the molecular basis of their functional role in the immune response. Therefore, we have...
Topics
- Amino Acid Sequence
- Animals
- Antibodies, Anti-Idiotypic
- Antibodies, Monoclonal
- Base Sequence
- Genes, Immunoglobulin
- HLA-DR Antigens
- Immunoglobulin Heavy Chains
- Immunoglobulin J-Chains
- Immunoglobulin Light Chains