Article
Identification of the amino acid residues contributing to monoclonal antibody-defined DQw1 epitopes.
Human immunology - 1 Jun 1991
Nordwig H, Kwok W W, Johnson J P
Abstract excerpt
The reactivity of monoclonal antibodies (mAbs) R1, S1, and S5, shown previously to recognize polymorphic epitopes on HLA-DQ molecules, have been found to correlate with the presence of certain DQB1 alleles. mAb S5 reacts with cells expressing DQB1*0503, 0601, 0602, 0603, or 0604 alleles while R1...
Topics
- Alleles
- Amino Acid Sequence
- Animals
- Antibodies, Monoclonal
- Binding Sites, Antibody
- Epitopes
- HLA-DQ Antigens
- HLA-DQ beta-Chains
- Humans
- Mice
- Molecular Sequence Data
- Polymorphism, Genetic
