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Article

Multiprotein transcription factor UAF interacts with the upstream element of the yeast RNA polymerase I promoter and forms a stable preinitiation complex.

Genes & development - 1 Apr 1996

Keys D A, Lee B S, Dodd J A, Nguyen T T, Vu L, Fantino E, Burson L M, Nogi Y, Nomura M

Abstract excerpt

Like most eukaryotic rDNA promoters, the promoter for rDNA in Saccharomyces cerevisiae consists of two elements: a core element, which is essential, and an upstream element, which is not essential but is required for a high level of transcription. We have demonstrated that stimulation of transcription by the upstream element is mediated by a multiprotein transcription factor, UAF (upstream activation factor)...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 8846924
DOI: 10.1101/gad.10.7.887

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Multiprotein transcription factor UAF interacts with the upstream element of the yeast RNA polymerase I promoter and forms a stable preinitiation complex.PMID 8846924Read ↗

Transcription of multiple yeast ribosomal DNA genes requires targeting of UAF to the promoter by Uaf30.Semantic proximity Read ↗

In vivo binding and hierarchy of assembly of the yeast RNA polymerase I transcription factors.Semantic proximity Read ↗

The cell cycle regulatory factor TAF1 stimulates ribosomal DNA transcription by binding to the activator UBF.Semantic proximity Read ↗

A system to study transcription by yeast RNA polymerase I within the chromosomal context: functional analysis of the ribosomal DNA enhancer and the RBP1/REB1 binding sites.Semantic proximity Read ↗

The HMG box-containing nucleolar transcription factor UBF interacts with a specific subunit of RNA polymerase I.Semantic proximity Read ↗

Hmo1 directs pre-initiation complex assembly to an appropriate site on its target gene promoters by masking a nucleosome-free region.Semantic proximity Read ↗

Nucleolar transcription factor hUBF contains a DNA-binding motif with homology to HMG proteins.Semantic proximity Read ↗

RRN6 and RRN7 encode subunits of a multiprotein complex essential for the initiation of rDNA transcription by RNA polymerase I in Saccharomyces cerevisiae.Semantic proximity Read ↗

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A single amino acid change in a pathway-specific transcription factor results in differing degrees of constitutivity, hyperinducibility and derepression of several structural genes.Semantic proximity Read ↗

Domains of the rat rDNA promoter must be aligned stereospecifically.Semantic proximity Read ↗

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