Article
Cytochrome P450IIE1 genetic polymorphisms, racial variation, and lung cancer risk.
Cancer research - 1 Dec 1992
Kato S, Shields P G, Caporaso N E, Hoover R N, Trump B F, Sugimura H, Weston A, Harris C C
Abstract excerpt
Cytochrome P450IIE1 is responsible for the activation of carcinogenic N-nitrosamines, benzene, urethane, and other low-molecular-weight compounds. Restriction fragment length polymorphisms (PstI and RsaI restriction enzymes) have been identified in the cytochrome P450IIE1 transcription regulatory...
Topics
- Alleles
- Baltimore
- Case-Control Studies
- Cytochrome P-450 CYP2E1
- Cytochrome P-450 Enzyme System
- Genotype
- Humans
- Japan
- Lung Neoplasms
- Odds Ratio
- Oxidoreductases, N-Demethylating
- Polymerase Chain Reaction
- Polymorphism, Genetic
- Racial Groups