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Article

Cytochrome P450IIE1 genetic polymorphisms, racial variation, and lung cancer risk.

Cancer research - 1 Dec 1992

Kato S, Shields P G, Caporaso N E, Hoover R N, Trump B F, Sugimura H, Weston A, Harris C C

Abstract excerpt

Cytochrome P450IIE1 is responsible for the activation of carcinogenic N-nitrosamines, benzene, urethane, and other low-molecular-weight compounds. Restriction fragment length polymorphisms (PstI and RsaI restriction enzymes) have been identified in the cytochrome P450IIE1 transcription regulatory region that may affect expression. This study describes the PstI and RsaI polymorphisms in different racial...

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PMID: 1423319

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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