Article
Association between the CYP2E1 polymorphisms and lung cancer risk: a meta-analysis.
Molecular genetics and genomics : MGG - 1 Apr 2015
Ye Xiang-Hua, Song Liang, Peng Ling, Bu Zhibin, Yan Sen-Xiang, Feng Jie, Zhu Xin-Li, Liao Xin-Biao, Yu Xue-Lin, Yan Danfang
Abstract excerpt
The previous, published data on the association between CYP2E1 RsaI (rs2031920), DraI (rs6413432) polymorphisms and lung cancer risk remained controversial. Hence, we performed a meta-analysis to investigate the association between lung cancer and CYP2E1 RsaI (5,074 cases and 6,828 controls from 34 studies), and CYP2E1 DraI (2,093 cases and 2,508 controls from 16 studies) in different inheritance models. Overall,...
Topics
- Adenocarcinoma
- Case-Control Studies
- Cytochrome P-450 CYP2E1
- Gene Frequency
- Genetic Association Studies
- Genetic Predisposition to Disease
- Humans
- Lung Neoplasms
